Dubai Police Genome Center

Select the case to work on Case —

🧭 Unidentified sample — infer the biogeographic ancestry (group task)

Step 1 — Impute the missing genotypes. The ancestry-informative SNP panel has gaps (?). Use the reference haplotype legend — alleles that are usually inherited together — and their population frequencies to fill each gap with the most likely base.
Step 2 — Run the ancestry analysis. With the panel complete, generate the ADMIXTURE plot and PCA, then decide which region of the world the person is most likely from.

Report your group's imputed bases and region call to your instructor, who holds the answer key.

STEP 1 Imputation — fill the missing bases

Reference haplotypes for this sample's likely source panel. Alleles in each row tend to be inherited together; the frequency is how common that haplotype is.

Gaps filled: 0/0

STEP 2 Ancestry analysis — ADMIXTURE & PCA

Fill every gap in Step 1 to unlock.

ADMIXTURE — ancestry composition

Unknown sample:

PCA — projection onto reference populations

How to read these:

ADMIXTURE — the coloured fractions are how much of the genome matches each reference ancestry. One dominant colour ≈ one main ancestry; two large colours ≈ admixed.

PCA — the gold ★ is your sample. The reference cluster it sits closest to is the most similar population; sitting between two clusters indicates admixture.

Deciding the call: if ONE component is clearly largest (roughly ≥70%) and the ★ sits inside a cluster → name that single region (minor components are normal). If TWO components are both large (each roughly 40–55%) and the ★ sits in the gap between two clusters → call it admixed, and say which two.

Your group's call — which region is this person most likely from?

📋 Your group's answers —