Dubai Police Genome Center

Select the case to work on Case —

🏥 Case file — work through it as a group

A patient has been sequenced at the Genome Center because of their symptoms. As a group, complete the two-step molecular diagnostics workflow, agree on a verdict, then report it to your instructor — who holds the key and will confirm whether you're right.

Step 1 — Call the variants. For each gene, compare the patient read to the reference, click the base that differs, and translate the codon to decide synonymous / missense / nonsense. If a gene matches the reference, mark “No variant”.
Step 2 — Interpret against the database. Look each gene up in the ClinVar-style database, then weigh classification + inheritance + zygosity to choose your verdict.

Show the codon → amino acid table (your translation key)

STEP 1 Sequencing — call the variants

Genes answered: 0/0

STEP 2 Clinical interpretation — compare to the database

Answer every gene in Step 1 to unlock. Then look each gene up and agree on a verdict.

📋 Your group's answers —

Read these to your instructor. Nothing here is graded — your instructor confirms what's right.

🏥 Case file — work through it as a group

STEP 1 Sequencing — call the variants

STEP 2 Clinical interpretation — compare to the database

📋 Your group's answers —

🔑 Answer key — instructor only